It's possible to make PDFs that look good on screen, but only if you accept the idea of generating separate versions for print and screen:
-- RonBean
If you're asking "why not use HTML", see the discussion on PdfSucks.
If you want to include the strong points of both, inside a Wiki Framework, see WikiBatics, a Wiki Project to show how Wiki can be used to compose any number of artifacts, including the authoring of a NewPage on WardsWiki, EddiesWiki, or other WikiLikeThing. -- DonaldNoyes.20110402