Hit back at Spam by reporting it.
- http://www.ftc.gov/bcp/conline/pubs/online/inbox.htm says "Send a copy of unwanted or deceptive messages to uce@ftc.gov. The FTC uses the unsolicited emails stored in this database to pursue law enforcement actions against people who send deceptive spam email."
also see
SpamCop for discussions on another service
CategorySpam