This term relates to the nowadays BuzzWord ScaleAbility?.
There are situations where adding more power to one machine or exchanging a machine with a more powerful one reach the limit of what is physically or economically feasible. Then, and I say only then, you should think about putting the load to be handled on more than one machine.
But remember, there are other ways to scale a system:
As you see, just by saying: let us scale the system you get into a much higher level of complexity. You get a system consisting of more computers performing less (at least in terms of user perception) because of the latency required by the additional communication and the coordination overhead involved.
Please think of that, when you next read the word ScaleAbility? or multi-tier.
That doesn't mean SeparationOfConcerns is not a good concept, but it shouldn't be blindly used to distribute functionality across deep chasms.
The big mainframe computers (I never used one) as all singular systems have an enormous benefit: if something goes wrong you know where to look (or who to blame).