A friendly & unassuming online comic; more humane than SluggyFreelance, but at the expense of less sharp barbs lying around...
http://freefall.purrsia.com/default.htm
Hosted by Purrsia (http://www.purrsia.com), which is the Internet home of a lot of other fine comics. This comic strip makes this Wikizen laugh out loud about one out of three strips, which is pretty good odds. Most of my favorite strips barely get a chuckle.